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twoday.net AGB

Yuk yuk...

Forget about the genome in today's Nature, the other articles of the special chimp issue seem a lot more interesting than the n-th partial sequencing of another mammal. The real question to me is whether we have improved the gene finding in mammalian genomes. Not that I think that the work is insignificant - but the findings in the genome papers always disappoint. We know the genome so well, what novelties are left to discover?

Btw, check this large scale clinical systems biology experiment from the Advance Online Publication pages.
Neil (guest) - 2005-09-01 09:31

Data needs questions

I know what you mean about disappointing genome papers. Incomplete drafts are an issue - you can learn a lot from a high quality draft, but doubts wil linger until completion. I guess people try to publish as early as they can for fear of being scooped.

It often seems that a few standard types of analyses are run, findings reported and then...that's all you hear from that genome.

My feeling is that people are not sure what to do with genome data. It's great that we have so much information, but that's only half the battle. What we need are interesting biological questions, particularly in comparative genomics. Perhaps many people have yet to develop the ability to formulate large scale, sophisticated queries of that kind.

spitshine - 2005-09-01 10:11

Getting scooped on chimp?

I do understand why we have multiple publications of the same genome - first you want to give people access and show them what the genome is like. On the other hand, as long as publications are an important reward for individual scientists, the many people doing most of the often dull work receive at least some credit.
The value of the genome sequence itself is out of questions; lets hope they receive the funding to finish as many as possible.

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Public Rambling - 2005-09-06 17:05

Chimp genome hype

Last week Nature journal dedicated... [read more]

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